Wednesday, July 24, 2013

Chapter 41 Some Reasons for High Cost of Cancer Drugs

Chapter 41


Floyd and I have been reading what Science Daily has recently been publishing about the Cost of Surviving Cancer.

Chapters 40 and 41  highlight two recent articles they published . . .


Physicians Identify Reasons for High Cost of Cancer Drugs, Prescribe Solutions



Science Daily  published this article on   Oct. 1, 2012

— A virtual monopoly held by some drug manufacturers in part because of the way treatment protocols work is among the reasons cancer drugs cost so much in the United States, according to a commentary by two Mayo Clinic physicians in the October issue of the journal Mayo Clinic Proceedings. Value-based pricing is one potential solution, they write.

"Cancer care is not representative of a free-market system, and the traditional checks and balances that make the free-market system work so efficiently in all other areas are absent when it comes to most cancer treatment," write authors, Mustaqeem Siddiqui, M.D., an oncologist and Vincent Rajkumar, M.D., a hematologist.

For example, when it comes to antibiotics to treat a given infection or over-the-counter painkillers, a physician or patient can choose between multiple drugs that do the same thing. But cancer drugs are administered to patients sequentially or in combination, creating a virtual monopoly for each drug. This is one of the principal reasons for the high cost of cancer therapy.

Other factors include the expense of drug development; the high price that patients and insurers are willing to pay for even modest improvement in outcomes; and a lack of regulations such as a cost effectiveness analysis to account for economic and value-based considerations in the drug approval and pricing process, the physicians write.

Solutions the authors recommend include:

* Value-based pricing that includes discrete metrics such as an incremental cost effectiveness ratio per quality-adjusted-life-years gained, as a result of a particular treatment. Quality-adjusted-life-years is an estimate of the number of years added to a patient's life by a specific drug intervention, adjusted for quality of life.

* A U.S. Food and Drug Administration mandate requiring drug companies to submit a value dossier when seeking drug approval. This information would give patients and physicians the ability to make better-informed decisions about treatment.

* Centers for Medicare and Medicaid Services powers to negotiate payments for cancer drugs.

* Improved national cancer guidelines providing evidence-based analysis of quality of life, mortality data, benefits, risks and cost for all possible treatment options.

* Monopoly rules to determine if a particular drug will operate in a monopoly situation. Such drugs would be subject to legally mandated or voluntary price controls in exchange for expedited approval or other remedy.

* Non-profit generic drug companies to manufacture and distribute generic cancer drugs at a very low cost.

Story Source:

The above story is based on materials provided by Mayo Clinic.

Journal Reference:
Mustaqeem Siddiqui, S. Vincent Rajkumar. The High Cost of Cancer Drugs and What We Can Do About It. Mayo Clinic Proceedings, 2012; 87 (10): 935 DOI:10.1016/j.mayocp.2012.07.007
Mayo Clinic (2012, October 1). Physicians identify reasons for high cost of cancer drugs, prescribe solutions. ScienceDaily. Retrieved July 24, 2013, from http://www.sciencedaily.com­/releases/2012/10/121001083212.htm


Floyd and I agree that some drug manufacturers hold a monopoly

You can decide if Science Daily and Floyd & I

 share your point of view . . . or not



Til’ we chat again, 

Remember  . . .

“We are all responsible for our wake and any influence it causes!”





"Leave a wake behind you, that you would want others to leave for you."




  Joe & Floyd



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